The Effectiveness of Thromboprophylaxis Therapy in Hypercoagulable Dogs and Cats

Presentation Description / Summary: Thromboprophylaxis therapy, both anticoagulant and antiplatelet medications, are commonly administered to hypercoagulable dogs and cats for their potential life-saving benefits. Unfortunately, it is difficult to predict the effectiveness of these medications. Although numerous diagnostic tests are available, veterinarians will commonly consider thromboprophylaxis therapy to have been successful if thrombosis or hemorrhage were not clinically detectable. Additionally, even if patients die, thromboprophylaxis therapy could be considered successful if the cause of death was not associated with thrombosis formation or excessive hemorrhage. However, in cases where thromboprophylaxis therapy is considered successful, the true risk of excessive thrombosis formation may be unknown. Based on the diagnosis and a perceived concern for hypercoagulability, thromboprophylaxis therapy is usually initiated, but that individual patient may have a minimal risk of thrombosis formation. But, because there is no clinical evidence of thrombosis formation or excessive hemorrhage, thromboprophylaxis therapy is considered successful, despite a questionable need for therapy. Based on our ongoing research, this session will review common anticoagulant and antiplatelet therapies and discuss if the current use of these medications is effective.